Welcome to the website of the Special Interest Group in Necrotizing Enterocolitis.


Necrotizing enterocolitis (NEC) is an acute gastrointestinal inflammatory disease that predominantly affects preterm babies. As birth rates and the survival of babies born extremely prematurely improve, NEC is growing in global relevance. It is a significant and complex clinical problem. NEC has high death rates and is associated with major long-term gastrointestinal and neurodevelopmental disabilities.

Greater international collaboration is needed to power research and to reduce the enormous burden this disease has placed upon families and healthcare systems. The aim of SIGNEC is to facilitate knowledge sharing, networking and collaboration to optimise research and improvements in practice around the world.

What is the Special Interest Group in Necrotizing Enterocolitis?
Information for professionals
Summaries and programmes from past events and select presentations.
Information for families
NEC explained in  guides for families.

The Big Little Warriors of Brazil

by Simone Rosito

My dream is to never have to operate on a baby with NEC again. Prof. Gail Besner

Chief, Dept.of Pediatric Surgery, Nationwide Children's Hospital, Columbus, USA


10.5.18 May 17 is NEC Awareness Day. Groups from around the world are uniting to raise awareness of this devastating disease. Please help us to protect babies by sharing information and consider making a donation to a NEC-focused nonprofit organization. SIGNEC has been delighted to work with our partners at the NEC Society, PGG and NEC UK to make this day happen! #NECday #preventNEC

Please note:

This website is intended to help health professionals and the public understand necrotizing enterocolitis and progress made in research into the disease. It is not a substitute for discussion with those responsible for the care of a baby. Every individual baby and clinical situation is unique. The ultimate judgement regarding a particular clinical procedure or treatment must be made by the clinician in the light of the clinical data presented by the patient and the diagnostic or treatment options available.

All presentations available to download from this website have been given at previous meetings of the Special Interest Group in Necrotizing Enterocolitis (SIGNEC). They appear by kind permission of the authors and Dr Minesh Khashu and may not be reproduced without their consent.  No other materials, or the SIGNEC logo, may be used or reproduced without the permission of Dr Minesh Khashu. All conference photographs by David Betteridge Photography.

While all reasonable efforts have been made to check the contents of external sites, links are not an endorsement of those sites.