Dr Minesh Khashu

Necrotizing enterocolitis (NEC) is an acute gastrointestinal inflammatory disease that predominantly affects preterm babies. As birth rates and the survival of babies born extremely prematurely improve, NEC is growing in global relevance. It is a significant and complex clinical problem. NEC has high death rates and is associated with major long-term gastrointestinal and neurodevelopmental disabilities.

Greater international collaboration is needed to power research and to reduce the enormous burden this disease has placed upon families and healthcare systems. The aim of the Special Interest Group in Necrotizing Enterocolitis is to facilitate knowledge sharing, networking and collaboration to optimise research and improvements in practice around the world.

This was the conference programme for 2018 and selected presentations will be available soon. Here are summaries and presentations from the 2017 conference.

What is the Special Interest Group in Necrotizing Enterocolitis?
Information for professionals
Summaries and programmes from past events and select presentations.
Information for families
NEC explained in  guides for families.
With Micah in my heart and the NEC Society in my hands.


Novel NEC therapy licensed for development shows promise for clinical trials.

Professor David Hackam, Garrett Professor and Chief of Pediatric Surgery at Johns Hopkins University School of Medicine in Baltimore, USA, announced at the sixth international SIGNEC conference that the world’s first NEC-specific therapy, C34, has just been licensed to a company for further development. It is hoped that it will soon receive approval by the US Food & Drug Agency (FDA) for clinical trials. More >

My dream is to never have to operate on a baby with NEC again. Prof. Gail Besner

Chief, Dept.of Pediatric Surgery, Nationwide Children's Hospital, Columbus, USA

Please note:

This website is intended to help health professionals and the public understand necrotizing enterocolitis and progress made in research into the disease. It is not a substitute for discussion with those responsible for the care of a baby. Every individual baby and clinical situation is unique. The ultimate judgement regarding a particular clinical procedure or treatment must be made by the clinician in the light of the clinical data presented by the patient and the diagnostic or treatment options available.

All presentations available to download from this website have been given at previous meetings of the Special Interest Group in Necrotizing Enterocolitis (SIGNEC). They appear by kind permission of the authors and Dr Minesh Khashu and may not be reproduced without their consent.  No other materials, or the SIGNEC logo, may be used or reproduced without the permission of Dr Minesh Khashu. All conference photographs by David Betteridge Photography.

While all reasonable efforts have been made to check the contents of external sites, links are not an endorsement of those sites.